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Tolerance Bio

Tolerance Bio’s Implanted iPSC-derived Thymic Organoids Enable In Vivo Positive Selection of Human T cells and Tumor Burden Reduction in Melanoma

By Portfolio News, Tolerance Bio
Patient-specific human immune system-bearing mouse model created by implanting human thymic cells derived from iPSC with Tolerance Bio’s proprietary process Human T cells educated in vivo by thymic organoids delayed melanoma tumor growth in a patient derived xenograft model Data support the development of Tolerance Bio’s thymic cells and pharmacological…
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Tolerance Bio and ZipCode Bio Announce Strategic R&D Collaboration

By Portfolio News, Tolerance Bio
Tolerance Bio and ZipCode Bio Announce Strategic R&D Collaboration to Advance Targeted Thymus Therapeutics   September 8, 2025 10:30 AM, PHILADELPHIA & BOSTON--(BUSINESS WIRE)--Tolerance Bio, a biopharmaceutical company pioneering innovative approaches to extending healthspan by preserving, restoring, and manipulating the function of the thymus, the master regulator of immune tolerance, and…
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Tolerance Bio, Inc. Announces Scientific Advisory Board and Completion of $20.2 Million Seed Round

By Portfolio News, Tolerance Bio
Tolerance Bio, Inc. Announces Scientific Advisory Board and Completion of $20.2 Million Seed Round to Advance Thymus-Based Therapies for Immune-Mediated Diseases   World-class leaders in the thymus, immunology, oncology, cell therapy, and drug development will inform and support the Company’s efforts to preserve, restore, and manipulate the thymus to address…
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Tolerance Bio, Inc. Launches With $17.2 Million in Seed Financing to Advance Thymus-Based Therapies for Immune-Mediated Diseases

By Portfolio News, Tolerance Bio
Tolerance Bio, Inc. Launches With $17.2 Million in Seed Financing to Advance Thymus-Based Therapies for Immune-Mediated Diseases Led by industry innovator Francisco Leon, M.D., Ph.D., Tolerance Bio is developing thymus preservation, regeneration, and manipulation platforms to prevent and treat immune diseases Financing led by Columbus Venture Partners, with participation by…
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